Tips

Ultra-Micro and Micro TipColumns

Ultra-Micro and Micro TipColumns are a simple and fast way to perform small sample preparation based on the physical properties of the sample. The columns consist of micro-pipette tips containing one of a wide range of available column materials contained by frits and/or cap. The sample can be applied to the top of the column or suctioned through the column using a micro-pipette. The sample is then purified according to size and shape, chemical composition, charge or other physiochemical properties by selecting the appropriate column material.

Advantages

• Fast, simple, easy to use
  
• Unrivaled range of column materials available
  
• No special equipment necessary; use standard pipette
  
• Suitable for samples from 10 to 25ml and 25 to 75 ml

PrepTip

PrepTip is a revolutionary new method for cleaning and concentrating proteins and other biological samples for further instrumental analysis. PrepTip’s unique, patented feature is that the interior walls of the tip are coated with the sample binding material. This interior coating technology makes PrepTip the only such product on the market, providing both speed and reliability. Since the tip opening is not plugged by the interior coating process, the sample can flow freely through the opening without back pressure. PrepTip can be used to clean or concentrate any biological sample since the interior walls of the tip can be coated with your choice of binding media. Different binding materials are available. Due to its unique features, sample preparation with PrepTip is very fast, simple and highly effective. PrepTip is welll suited for a range of applications including mass spectrometry, HPLC and automated sample preparation methods.

Advantages

• Protein or peptide purification
• Salt removal
• Detergent removal
• Mass spectrometry
• Affinity purification
• Glycoprotein and glycopeptide purification
• MALDI-TOF
• HPLC
• High performance Capillary Electrophoresis (HPCE)

ProTip

ProTip is a new method for cleaning and concentrating protein samples for further instrumental analysis. ProTip offers the same easy sample flow of our PreTip, but contains a small quantity of a highly effective hydrophilic polymer material. The binding capacity of the polymer used in ProTip is 5 to 10 times higher than that of silica-based materials. This polymer binds protein in the presence of organic solvents but does not binds impurities, such as salts and detergents in the samples. After the protein is bound to the polymer it can be easily eluted in an acqueous solution, making purification and concentration of biological samples fast, simple and highly effective.

Advantages

• Fast, simple, easy to use
• Highly effective, non-silica based hydrophilic polymer material
• Easy, rapid flow of sample due to the unobstructed tip opening of ProTip
• Effective for small samples (even with volumes less than 1ml)
• Tip sizes available to suit a range of sample volumes
• No special equipment necessary, uses standard micro-pipette tips
• Suitable for use with single or multi-channel pipetting devices