Transcription Factor proteins play a pivotal role in the process, acting as regulators of gene expression, specifically regulating the activation of transcription in the eukaryotic nucleus. They do this through binding, either by themselves, or by controlling the binding of other proteins to the promoter and enhancer sequence elements of the genes to be transcribed. As such master regulators, Transcription Factors are biologically interesting targets to many researchers.
Delivering Tools for Transcription Factor Research
Panomics has developed a comprehensive suite of tools to aid in Transcription Factor research. Its comprehensive profiling assays, including a unique multiplex assay, allows researchers to monitor the activities of many Transcription Factors simultaneously.
Changes in Transcription Factor activity in response to environmental or physiological stimulus can be indicative of changes to specific signaling pathways and can be used as biomarker fingerprints or signatures. Thus, studies of TFs are particularly useful for cancer
researchers, physiologists, immunologists and virologists.
The comprehensive and growing ELISA menu for the most important Transcription Factors are the most sensitive on the market, and all products have the same simple assay workflow.
The use of Stable Cell Lines is becoming important as more contextual cell-based assays are being developed, particularly in the pharmaceutical industry. The range of stable cell lines help with this paradigm shift in assay development.
Panomics also offers a comprehensive range of EMSA Gel-Shift assays and unique reporter assays.
